This stops the Salesforce CTI adapter from working.
As the Chrome script blocker cannot be configured to always allow content from a particular site, Salesforce advise it is currently necessary to disable the blocker.
Adding this command line parameter does not remove all security from the web browser. It just allows insecure content (e.g. links to non-https protocols) to co-exist on the same web pages as secure content (https pages). The click-to-dial method uses the Protocol Handler "Flexor" to pass the phone number to Flexor which is considered to be insecure content.